KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDAC5
All Species:
17.88
Human Site:
S173
Identified Species:
39.33
UniProt:
Q9UQL6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQL6
NP_001015053.1
1122
121992
S173
I
L
R
N
K
E
K
S
K
E
S
A
I
A
S
Chimpanzee
Pan troglodytes
XP_511542
1219
132437
S270
I
L
R
N
K
E
K
S
K
E
S
A
I
A
S
Rhesus Macaque
Macaca mulatta
XP_001100255
1188
128730
S239
I
L
R
N
K
E
K
S
K
E
S
A
I
A
S
Dog
Lupus familis
XP_856949
1134
123233
S182
S
L
R
N
K
E
K
S
K
E
S
A
I
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2V6
1113
120924
S164
I
L
R
N
K
E
K
S
K
E
S
A
I
A
S
Rat
Rattus norvegicus
Q99P99
1077
118634
K159
Q
Q
L
K
N
K
E
K
G
K
E
S
A
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510939
1082
119892
K163
Q
Q
L
K
N
K
E
K
G
K
E
S
A
V
A
Chicken
Gallus gallus
P83038
1080
119449
K159
Q
Q
L
K
N
K
E
K
G
K
E
S
A
V
A
Frog
Xenopus laevis
Q9YGY4
596
67288
Zebra Danio
Brachydanio rerio
Q6PBI4
582
65098
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17323
816
88964
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.8
93.8
95
N.A.
94.6
58.4
N.A.
59
59.7
28
27
N.A.
N.A.
N.A.
30.7
N.A.
Protein Similarity:
100
92
94.1
96.8
N.A.
96.1
71.6
N.A.
73
72.9
38.6
37.2
N.A.
N.A.
N.A.
44.6
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
0
0
0
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
33.3
N.A.
33.3
33.3
0
0
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
46
28
46
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
46
28
0
0
46
28
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
28
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
37
0
0
0
0
0
0
0
0
0
0
0
46
0
0
% I
% Lys:
0
0
0
28
46
28
46
28
46
28
0
0
0
0
0
% K
% Leu:
0
46
28
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
46
28
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
28
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
46
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
46
0
0
46
28
0
0
46
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
28
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _